Antibiotics that inhibit bacterial protein synthesis target the ribosomal subunits (30s & 50s)
Binding to the 30s ribosomal subunit-
1. Aminoglycoside (Streptomycin)
2. Tetracycline
Binding to the 50s ribosomal subunit-
1. Chloramphenicol
2. Clindamycin
3. Macrolides (Erythromycin)
4. Linezolid
Reference:
1. Essentials of Medical Pharmacology, KD Tripathi, 8th edition, P. No. 790, 793, 807
2. Diseases of ear, nose and throat, PL Dhingra & Shruti Dhingra, 7th edition, P. No. 173