|
Drug |
Gene |
|
Isoniazid (INH) |
• katG (Catalase-peroxidase) • oxyR (Oxidative stress regulator) • ahpC (Alkyl hydroperoxide reductase) |
|
Rifampicin (RIF) |
• rpoB (RNA polymerase subunit B) |
|
Pyrazinamide (PZA) |
• pncA (Pyrazinamidase) |
|
Ethambutol (EMB) |
• embCAB (Arbinosyl transferase) |
|
Streptomycin |
• rpsL (Ribosome protein subunit 12) • rrs (16 ribosomal RNA) |
|
INH-ETH |
• inhA (Enoyl acyl carrier protein reductase) |
|
Fluoroquinolone (FQ) |
• gyrA (DNA gyrase A) |
Gene’s involved in anti-tuberculosis drug resistance
Pharmacology
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