|
Feature |
Hunter Syndrome (MPS II) |
Hurler Syndrome (MPS I) |
|
Inheritance |
X-linked recessive (affects males) |
Autosomal recessive |
|
Deficient Enzyme |
Iduronate-2-sulfatase |
α-L-Iduronidase |
|
Accumulated Substances |
- Dermatan sulfate - Heparan sulfate |
- Dermatan sulfate - Heparan sulfate |
|
Ophthalmic Findings |
No corneal clouding |
Corneal clouding present |
Hunter and Hurler syndrome
Biochemistry
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