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Second messengers mediating hormonal function

Physiology
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Secondary messengers- 

1. cAMP
2. cGMP 
3. Cell membrane phospholipid (IP3 & DAG)- PLC
4. Calcium ion

 

cAMP

PLC 

• Angiotensin ll (epithelial cells)

• Angiotensin ll (Vascular smooth muscle)

• Vasopressin (V2 receptor, epithelial cells)

• Vasopressin (V1 receptor, vascular smooth muscle)

• Catecholamines (Beta-receptor); Epinephrine 

• Catecholamines (Alpha-receptor)

Anterior pituitary hormone-

• ACTH

• LH 

• FSH

• TSH

• hCG

Posterior pituitary hormone-

• Oxytocin

 

Hypothalamic releasing 

• TRH (Thyrotropin releasing hormone)

• GnRH (Gonadotropin)

• GHRH (Growth hormone)