Dermatology

Pemphigus vulgaris

Leave a Comment / Dermatology / TCML / February 26, 2026

• Type: Autoimmune blistering disorder • Autoantibodies: Against Desmoglein-3 (mucosa) ± Desmoglein-1 (skin) — components of desmosomes • Hypersensitivity type: Type 3 Hypersensitivity (Ag-Ab complex) • Blister type- Flaccid, Intraepidermal blisters Pemphigus group of disorders Pemphigoid group of disorders Bullae Flaccid bullae Tense bullae (because whole epidermis is present in bulla covering so bulla is tight / tense) Bullae […]

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Scabies

Dermatology / TCML / September 17, 2023 / crotamiton, derma, Dr. Pawan nagar, inicet, mbbs, neet pg, next, permethrin, Scabies, tcml, The Charsi of Medical literature

Highlights: 1. Caused by sarcoptes scabei (Itch mite). 2. Pathognomonic sign – Burrow 3. Hebra circle 4. Treatment – Scabicides (Kill mite) and Antihistamines (Reduce itching) Reference: 1. GHAI Essential Pediatrics, Vinod K Paul and Arvind Bagga, 9th Edition, P. No. 699, 700

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