TNM staging of breast cancer

Types of TNM staging: (Mnemonic- My CPR

• mTNM- for multiple primary tumors at same site

• yTNM- Staging is done patient has received neoadjuvant chemotherapy

• ypTNM- Pathological staging done after neoadjuvant chemotherapy 

• cTNM- for clinical staging

• pTNM- for pathological staging

• rTNM- for recurrent tumors 

Stage

Features

Tis

• DCIS

• Paget’s disease of breast

T1

≤2cm

(T1a ≤0.5 cm, T1b >0.5-1 cm, T1c >1-2 cm)

T2

>2 – ≤5 cm

T3

>5 cm

T4

Tumor of any size

T4a (ander)

C – Chest wall

Extension to chest wall- (Sir)

• Serratus anterior

• Intercostal muscles

• Ribs

Note: Pectoralis major / minor muscle not include.

T4b (bahar)

U – Ulcer

Skin changes (on same breast)- (SURE)

• Satellite nodule

• Ulcer

• Edema, including Peau d’orange

(PYQ: INICET May 2025)

T4c

R – Required both

T4a + T4b

T4d

E – Inflammation

Inflammatory breast cancer

(Typical ≥1/3rd breast skin involvement)

Node

Description

N1

Metastasis to ipsilateral 

mobile Axillary LN level I & II

N2

N2a: Metastasis to ipsilateral

fixed / matted Axillary LN level I & II

N2b: Clinically apparent Internal mammary nodes

N3

N3a: Metastasis to ipsilateral Infra-clavicular LN

N3b = N2a + N2b

N3c: Metastasis to ipsilateral Supra-clavicular LN

Internal mammary LN-

Clinically not palatable 
Detect on radiology (USG, Mammography, MRI)

Note- Sentinal node for breast cancer: Anterior LN / Giuliano node (Level I / Lateral to pectoralis minor) 

Metastasis

 

M0

No distant metastasis

M1

Distant metastasis: m/c in bones (lumbar
vertebrae)

or

Any nodal metastasis on contralateral
side (opposite side)

Stage

Description

Stage I

T1 N0

Stage IIa

T2 N0, T1 N1

Stage IIb

T3 N0, T2 N1

Stage IIIa

T1 N2*, T3 N2, T2 N2, T3 N1

Stage IIIb

T4, N0-2

Stage IIIc

any T, N3

Stage IV

any T, any N, M1

Surgical staging

 

Early breast cancer (EBC)

Stage I

Stage IIa

Stage IIIb

Locally advanced breast
cancer (LABC)

Stage IIIa

Stage IIIb

Stage IIIc

Metastatic cancers

Stage IV

 

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